According to the description given above, IMR exhibits several unique merits, as described below. 

Firstly, the unbound to-be-detected bio-molecules and magnetic nanoparticles are not necessarily to be removed. They are still in the reagent. So, the assay process of IMR is simple because of wash-free processes. 

Secondly, only one kind of bio-probe is used. 

Thirdly, IMR is a direct and homogeneous assay, which usually shows high reliability and sensitivity. Especially, magnetic nanoparticles show high surface-to-volume ratio. The binding area between antibodies and to-be-detected bio-molecules is extremely large, which results in a high sensitivity. 

Fourthly, the non-specific binding between the bio-probes and non-target bio-molecules is highly suppressed. The mechanism for the high suppression in non-specific binding is briefly explained as follows. Magnetic nanoparticles oscillate with the external ac magnetic fields when detecting the χac of the magnetic reagent. Both target and non-target bio-molecules bound with bio-probes on the oscillating magnetic nanoparticles experience centrifugal forces. At high oscillating frequencies, the centrifugal force is enhanced. Once the centrifugal force is stronger than the binding force between the bio-probes and non-target bio-molecules, the nonspecific binding is broken down. However, the centrifugal force must be weaker than the specific binding force between bio-probes and to-be-detected bio-molecules. As a result, the cross reactions are inhibited for IMR.

Fifthly, because the amount of reduction in χac can be accurately measured to correspond to the concentration of the to-be-detected bio-molecules, the concentration of the bio-molecules can thus be measured quantitatively. 
Several papers have demonstrated that IMR can be applied to assay proteins, viruses, chemicals, and nucleic acids once suitable bio-probes are immobilized onto the magnetic nanoparticles.